Exercise guidelines for cancer survivors
For the rising number of cancer survivors worldwide, there's growing evidence that exercise is an important part of recovery. But how much, and what type of exercise, is needed?
Read moreDiseases and Conditions
Failure of mitochondrial quality control causes heart disease
Mutations in the gene that encodes a protein called ANT cause a variety of conditions, such as heart disease, but the underlying mechanism of how these mutations trigger disease has been unclear. Researchers discovered that ANT is critical for a quality control process called mitophagy — which helps to ensure the integrity of the mitochondria network — and found that mutations that lead to a defective quality control system cause heart disease.
Read moreSmoke signals: Study shows path linking nicotine addiction to increased risk for diabetes
Researchers have discovered a circuit in rats that links cigarette smoking and the risk of developing type 2 diabetes, according to a new study.
Read moreAcaí berry extracts fight malaria in mice
Despite humanity's best efforts to eradicate malaria, the disease struck more than 200 million people in 2017, according to the World Health Organization. Worse yet, the parasite that causes malaria is developing resistance to many antimalarial drugs, including the mainstay, chloroquine. Researchers are actively searching for new treatments, and now, a group have found that acaí berry extracts can reduce parasites in the blood and prolong the survival of infected mice.
Read morePioneering cell therapies for non-responders to current immunotherapies
New research signposts a new, less invasive approach to identify killer T lymphocytes in patients with gastrointestinal tumors with low mutational burden who are refractory to approved immune-based treatments.
Read moreNew marker for tumor aggression in neurofibromatosis type 1
A new study of tumor samples from people with the rare genetic syndrome neurofibromatosis type 1 (NF1) has uncovered novel molecular clues about which tumors are most likely to be aggressive in those with NF1. According to the researchers, the clues could advance the search for more customized and relevant treatments that spare patients exposure to treatments unlikely to work.
Read moreDiabetes: A next-generation therapy soon available?
Insulin is normally produced by pancreatic beta cells. In many people with diabetes, pancreatic cells are not functional, causing a chronic and potentially fatal insulin deficiency that can only be controlled through daily insulin injections. However, this approach has serious adverse effects. In order to improve therapy, researchers have identified a protein called S100A9 which seems to act as a blood sugar and lipid regulator while avoiding the most harmful side effects of insulin.
Read moreOxygen in hyperbaric chamber provides relief after radiotherapy
Hyperbaric oxygen therapy (HBOT) can relieve self-reported symptoms and side-effects of radiotherapy against cancer in the pelvic region, a study shows. After 30-40 sessions in a hyperbaric chamber, many patients experienced reductions in bleeding, urinary incontinence, and pain alike.
Read moreScientists develop test for uncommon brain diseases
Scientists have developed an ultrasensitive new test to detect abnormal forms of the protein tau associated with uncommon types of neurodegenerative diseases called tauopathies. This advance gives them hope of using cerebrospinal fluid, or CSF — an accessible patient sample — to diagnose these and perhaps other, more common neurological diseases, such as Alzheimer's disease.
Read moreSequencing African genomes yields new data resource with broad applicability
By collaborating globally in a new, large-scale effort, researchers have made strong progress in sequencing genomes from regions and countries across Africa. These findings will enable more broadly representative and relevant studies ranging from basic through clinical genetics.
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