Scientists describe a previously unknown disorder of the immune system: in a distinct subset of immune cells from patients with primary immunodeficiency, cellular respiration is significantly increased. This cellular metabolic overactivity leads to inflammation.
Read moreWhile the medical community agrees immune cells inside a tumor leads to improved health outcome, for a subset of colorectal cancer patients, having too much of a good thing is a strong predictor of disease recurrence and reduced chances of survival. Scientists identify patients who could benefit from immunotherapy. This is the first report of immune infiltrated tumors with poor health outcomes and is counter to the standard belief in the field.
Read morePatients who attend 'Heart School', as almost every patient in Sweden is invited to do after a first heart attack, live longer than non-participating patients.
Read moreResearchers say they have evidence that hospital emergency departments (EDs) worldwide may be key strategic settings for curbing the spread of HIV infections in hard-to-reach populations if the EDs jump-start treatment and case management as well as diagnosis of the disease.
Read moreNew research shows that specialist analysis of the lens in the eye can predict patients with type 2 diabetes and impaired glucose tolerance (IGT) (also known as prediabetes, a condition that often leads to full blown of type 2 diabetes).
Read moreWhat role does fate play when it comes to the 145,000 people diagnosed with cancer each year in Australia and 125,000 people in Vietnam?
Read moreScientists have revealed close-up details of a vital molecule involved in the mix and match of genetic information within cells — opening up the potential to target proteins of this family to combat cancer's diversity and evolution.
Read moreA new study unveils a new, machine-learning derived model that can predict, with a high degree of accuracy, future heart failure among patients with diabetes.
Read moreA new study identifies specific locations where medication and harm reduction services for people with opioid use disorder should be available in order to have the greatest impact on reducing opioid overdose deaths. The data show that more than half of those who died of an opioid overdose in Massachusetts encountered the health care, public health and/or criminal justice systems within the 12 months prior to their fatal overdose.
Read moreIt's long been known that our immune cells mix and match bits of genetic code to make new kinds of antibodies to fight newly encountered threats. But how these different gene segments come together has been a mystery. A study provides the answer, showing how the classic process of V(D)J recombination makes use of chromatin looping to gather the segments to be spliced.
Read more