For hospitalized patients with fungal infections, specialists save lives

Fungal bloodstream infections are responsible for the deaths of more than 10,000 people every year. New research shows that the death rate can be reduced by 20% if infectious disease specialists oversee care of such patients.

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First systematic review and meta-analysis suggests artificial intelligence may be as effective as health professionals at diagnosing disease

Artificial intelligence (AI) appears to detect diseases from medical imaging with similar levels of accuracy as health-care professionals, according to the first systematic review and meta-analysis, synthesizing the available evidence from the scientific literature.

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Some parents pass on more mutations to their children than others

Everyone is a mutant but some are prone to diverge more than others, report scientists. A new study shows the number of mutations a child has compared to her parents varies dramatically with some people being born with twice as many as others, and that characteristic runs in families.

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Discovery of how colorectal cancer drug works will help more patients

Some colorectal cancer patients with a certain gene mutation benefit from a chemotherapy drug called cetuximab, although the mechanism of how this drug worked was unknown. Scientists have combined computational biology with experimental investigations to discover, for the first time, the mechanism for why these patients respond to cetuximab, which will help doctors identify more effective, targeted treatment plans for people diagnosed with colorectal cancer.

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Quality control in immune communication: Chaperones detect immature signaling molecules

The cells of our immune system constantly communicate with one another by exchanging complex protein molecules. A team has now revealed how dedicated cellular control proteins, referred to as chaperones, detect immature immune signaling proteins and prevent them from leaving the cell.

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