In a study of 115,803 individuals, the authors have identified 233 sites or loci in the human genome that contribute to the onset of MS. This is the largest study to date in MS.
Read moreFor the last 60 million years, fungus-growing ants have farmed fungi for food. In their cultivation of those fungi, they've successfully relied on bacteria-produced antimicrobial ingredients to protect their crops from other species of parasitic fungi. Now, researchers say they are looking to these ants to find new ways to stop or slow the evolution of antibiotic resistance that now presents a threat to modern medicine.
Read moreThe Global Program to Eliminate Lymphatic Filariasis delivers mass drug administration to 500 million people each year, and adverse events are common following treatment. Now, researchers have reported that certain changes in gene expression are associated with these adverse events.
Read moreThe first cell atlas of the human kidney's immune system has been created after scientists mapped nearly 70,000 individual kidney cells from early life and adults. Researchers generated the atlas and used it to map immune cells in the kidney. This shows for the first time how the kidney's immune system develops during early life, and strengthens after birth and as we mature into adults, with implications for tackling kidney disease and transplant rejection.
Read moreInvestigators have pinpointed a molecular defect that seems almost universal among patients with Parkinson's disease and those at a high risk of acquiring it.
Read moreResearchers have designed a field training equipment for short-range air defense systems, which imitates the natural conditions of missile defense including detection, tracking and destruction of the target without actually using the real missile in the training.
Read moreAdolescent acne does not always result in a pathological condition; rather, it may be a natural, transient inflammatory state occurring when the maturing facial skin is exposed to new microbes and enhanced production of an oily substance called sebum. Researchers argue that their novel framework suggests that the development of new treatments should focus on promoting mechanisms that restore homeostasis between facial skin and its microbial and chemical milieu.
Read moreA randomized clinical trial of targeted, high-dose radiation for men with oligometastatic prostate cancer has shown the treatment to be an effective and safe option for patients who wish to delay hormone-suppression therapy. The phase II trial found that radiation therapy can generate an immune system response not previously believed possible in this type of cancer.
Read moreThere is a risk of every fourth heart examined for possible donation being dismissed as unusable due to stress-induced heart failure. But this condition, according to new research, has no bearing on the outcome of a transplant. These results open the way for up to 30% more heart transplant.
Read moreThere's no question that as body weight increases, so too does blood pressure. Now, in a study of mice, researchers have revealed exactly which molecules are likely responsible for the link between obesity and blood pressure. Blocking one of these molecules — a signaling channel that's found in a tiny organ on the side of your neck — effectively lowers blood pressure in obese mice.
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