Cheap, quick test identifies pneumonia patients at risk of respiratory failure or sepsis

Researchers have now identified specific fragments of genetic material that play a role in the development of respiratory failure and sepsis in pneumonia patients. The findings could enable doctors to test quickly for these biological markers when a patient is admitted to hospital with pneumonia, so that they could anticipate complications and provide more intensive support and monitoring.

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Doctor offers unique perspective as father of a child with rare genetic disease

From a professional standpoint, Nathan Hoot, MD, Ph.D., understands the value of medical research that leads to new, groundbreaking drugs in the treatment of rare diseases. And as an emergency medicine physician, he's familiar with adjusting ventilators and managing patients' airways. But the magnitude of these matters also weigh on Hoot personally — as the father of a child with a rare genetic disease.

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Protozoans and pathogens make for an infectious mix

The new observation that strains of V. cholerae can be expelled into the environment after being ingested by protozoa, and that these bacteria are then primed for colonization and infection in humans, could help explain why cholera is so persistent in aquatic environments. The disease-causing bacteria are protected in the protozoan gut and ejected into the environment in membrane-bound expelled food vacuoles (EFVs).

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Vitamin C therapy linked to better survival rates after sepsis

New research suggests that patients with sepsis and septic lung injury could have a better chance of survival and recover more quickly when treated with vitamin C infusions. On average, the vitamin C group spent three fewer days in the ICU at day 28 and a week less in the hospital overall by day 60 than the placebo group.

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Barrier to rural opioid treatment: Driving distance to methadone clinics

People who live in rural counties in five states heavily affected by the opioid epidemic must drive longer distances to obtain methadone, a treatment for opioid addiction, compared to individuals from urban counties, say researchers. Their study suggests these long drive times in rural counties could be reduced by making methadone more accessible in primary care clinics.

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For the first time, professor observes crystallized iron product, hemozoin, made in mammals

For the first time ever, a professor has observed a crystallized iron product called hemozoin being made in mammals, with widespread implications for future research and treatment of blood disorders. Findings could be used to treat sickle cell disease and malaria patients, while opening up diverse research avenues across immunology, parasitology, neuroscience, microbiology, and even urology.

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