Administered within hours of an attack, the potential drug would prevent scarring that can lead to heart failure. For the study, the researcher used a drug that targets a key component of the cellular clock mechanism. The medication disrupts expression of genes that trigger adverse immune responses after a heart attack. When mice were given the drug after a heart attack, they were found to have less inflammation and improved cardiac repair.
Read moreSubstantial variation exists between general practices in uptake of new prescribing guidance, with important implications for patient care and health expenditure, finds the largest analysis of its kind.
Read moreResearch into the pathology of vaping-associated lung injury is in its early stages, but a study finds that lung injuries from vaping most likely are caused by direct toxicity or tissue damage from noxious chemical fumes.
Read moreStudy results help clarify how to safely prevent tuberculosis (TB) in women living with HIV who are pregnant or have recently given birth, are taking antiretroviral therapy, and live where TB is highly prevalent.
Read morePeople living with HIV who received kidney transplants from deceased donors with HIV had high rates of overall survival and kidney graft survival after five years, according to an observational study. The investigators followed 51 study participants with HIV who received kidney transplants from deceased donors with HIV in South Africa.
Read moreEvery year in the United States, about 7,500 people die while waiting for an organ transplant, and that number is expected to increase in coming years as demographics shift.
Read moreResearchers have uncovered a key step in how the human body metabolizes sugar, which could lead to better treatment and prevention of heart disease, obesity and Type 2 diabetes.
Read moreA multistakeholder coalition has issued clinical recommendations for the optimal prevention of secondary fracture among people aged 65 years and older with a hip or vertebral fracture — the most serious complication associated with osteoporosis.
Read moreYoung adults who experience annual income drops of 25% or more may be more at risk of having thinking problems and reduced brain health in middle age, according to a new study.
Read moreA new study is the first to report evidence that nonsteroidal anti-inflammatory drugs (NSAIDs) like aspirin may lessen the adverse effects of air pollution exposure on lung function. The researchers found that the use of any NSAID nearly halved of the effect of PM on lung function, with the association consistent across all four weekly air pollution measurements from same-day to 28 days prior to the lung function test.
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