Losing weight — and keeping it off — linked to cardiometabolic benefits
People who lose weight and keep it off can stabilize or even improve their cardiometabolic risk factors compared to people who regain weight, finds a new study.
Read moreDiseases and Conditions
Paclitaxel-coated devices are safe for unblocking arteries in lower limbs, study suggests
A study of nearly 65,000 people suggests that devices coated with a drug called paclitaxel that are used for widening blocked arteries in legs and feet are safe and not linked to an increase in deaths — a finding that contradicts smaller studies that led to the FDA issuing a safety alert about the use of paclitaxel-coated stents and balloons for arterial revascularization in the lower limbs in January 2019.
Read moreInnovative pancreatic cancer treatment may rev up immune system
A research team reports that combining a type of radiation therapy with immunotherapy not only cures pancreatic cancer in mice, but appears to reprogram the immune system to create an 'immune memory' in the same way that a vaccine keeps the flu away. The result is that the combination treatment also destroyed pancreatic cells that had spread to the liver, a common site for metastatic disease.
Read moreInsights on treatment and prognosis of male breast cancer
A recent analysis reveals that treatment of male breast cancer has evolved over the years. In addition, certain patient-, tumor-, and treatment-related factors are linked with better survival.
Read morePharmacists provide patient value in team-based care
As part of an innovative model, pharmacists manage the care of patients with chronic diseases such as asthma, diabetes and hypertension.
Read moreDrug can extend survival rates for heart failure patients
Blood pressure medication can prevent fluid retention and muscle wasting in heart failure.
Read moreNew addiction treatments hold promise for stemming the opioid crisis
Concerns over the opioid epidemic have sparked a strong scientific interest in why some people become addicted while others don't. Now, researchers are proposing novel treatment strategies that could help prevent abuse of opioids and other substances.
Read moreMapping normal breast development to better understand cancer
Breast cancer is one of the most prevalent cancers, and some forms rank among the most difficult to treat. Its various types and involvement of many different cells makes targeting such tumors difficult. Now, researchers have used a state-of-the-art technology to profile each cell during normal breast development in order to understand what goes wrong in cancer.
Read moreNew approach for modern power grids that increases efficiency, reduces cost
Scientists have developed a novel approach to allow for a small, well-defined risk of constraint violation to overcome the challenges that come with conservative current approaches used in modern power grids.
Read moreNew mechanism in the liver helps prevent invasive fungal infections
An expert in intravital microscopy is making breakthroughs in invasive fungal infections. He has discovered a pathway by which liver macrophages capture fungi before dissemination to target organs like the brain. This not only provides an explanation as to why individuals with liver disease have enhanced risk of fungal infection, but also points to therapeutic options to prevent these infections, which kill 1.5 million people annually.
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