Colon Cancer – Page 8 – PossibleThreat Articles

Discovery of novel cancer signaling mechanism and design of new anticancer compound

September 23, 2019 0 Comments Brain Tumor, Breast Cancer, Cancer, Colon Cancer, Leukemia, Lung Cancer, Lymphoma, Skin Cancer

Active mutations of a certain signaling receptor protein called KIT tyrosine kinase are found in several cancers, such as acute myeloid leukemia (AML). However, the different locations in the AML cells where KIT induces cancer-specific signaling remain unclear. Now, a group of scientists has aimed to answer this question by using a newly synthesized compound (along with other existing ones) that targets intracellular transport, which may offer an attractive strategy to combat cancer.

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Do the costs of cancer drugs receive enough attention?

September 23, 2019 0 Comments Cancer, Colon Cancer, Diseases and Conditions, Leukemia, Lung Cancer, Personalized Medicine, Pharmaceuticals, Pharmacology

A recent analysis from Canada found that information on health-related quality of life is often not collected for investigational cancer drugs or used to calculate the balance of costs and benefits of these drugs when they are submitted for reimbursement.

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Novel regulator of mitochondrial cell death reveals a promising target for cancer therapy

September 19, 2019 0 Comments Brain Tumor, Breast Cancer, Cancer, Colon Cancer, Leukemia, Lung Cancer, Ovarian Cancer, Prostate Cancer

Researchers have described the role of mitochondrial fission factor (MFF) in controlling survival of cancer cells, suggesting the protein could represent a promising therapeutic target.

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Evidence underpinning approval of new cancer drugs raises questions

September 19, 2019 0 Comments Breast Cancer, Cancer, Colon Cancer, Diseases and Conditions, Leukemia, Lung Cancer, Ovarian Cancer, Pharmacology

Around half of trials that supported new cancer drug approvals in Europe between 2014 and 2016 were judged to be at high risk of bias, which indicates that treatment effects might have been exaggerated, concludes a new study.

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Combination therapies could help treat fatal lung cancers

September 18, 2019 0 Comments Brain Tumor, Breast Cancer, Cancer, Colon Cancer, Lung Cancer, Lung Disease, Lymphoma, Skin Cancer

Combining a new class of drug with two other compounds can significantly shrink lung tumors in mice and human cancer cells, new research shows. The study looked at G12C KRAS inhibitors, a new type of drug that targets a specific mutation that can cause cells to multiply uncontrollably and lead to fast-growing cancers.

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New drug target in fight against cancer

September 18, 2019 0 Comments Brain Tumor, Breast Cancer, Cancer, Colon Cancer, Diseases and Conditions, Leukemia, Lung Cancer, Lymphoma

Researchers have discovered how a cancer-linked version of the protein mitoNEET can close voltage-dependent anion channels (VDAC), primary gateways in the outer surface of mitochondria. The researchers detail how mitoNEET regulates VDAC, and they show that the interactions between the two proteins could be disrupted by a drug that targets VDAC.

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Cancer cells turn to cannibalism to survive chemotherapy, study suggests

September 18, 2019 0 Comments Brain Tumor, Breast Cancer, Cancer, Colon Cancer, Leukemia, Lung Cancer, Lymphoma, Prostate Cancer

Researchers have discovered that some cancer cells survive chemotherapy by eating their neighboring tumor cells. The study suggests that this act of cannibalism provides these cancer cells with the energy they need to stay alive and initiate tumor relapse after the course of treatment is completed.

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Psoriasis drug target offers potential for osteosarcoma

September 18, 2019 0 Comments Breast Cancer, Cancer, Colon Cancer, Diseases and Conditions, Leukemia, Lung Cancer, Osteoporosis, Skin Cancer

A treatment for psoriasis could be repurposed to treat a rare but aggressive form of youth cancer, new findings suggest.

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Radiation may lower potential for side effects of CAR T therapy in non-hodgkin's lymphoma

September 18, 2019 0 Comments Colon Cancer, Diseases and Conditions, Gene Therapy, Lymphoma, Medical Imaging, Personalized Medicine, Today's Healthcare, Wounds and Healing

Treating non-Hodgkin's lymphoma (NHL) patients with radiation therapy as an additional treatment while they wait for their CAR T cells to be manufactured may reduce the risk of CAR T therapy side effects once it is administered.

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Novel anti-cancer nanomedicine for efficient chemotherapy

September 17, 2019 0 Comments Batteries, Cancer, Colon Cancer, Electronics, Lung Cancer, Materials Science, Nanotechnology, Prostate Cancer

Researchers have developed a new anti-cancer nanomedicine for targeted cancer chemotherapy. This new nano-tool provides a new approach to use cell-based nanomedicines for efficient cancer chemotherapy.