Decades-long drop in breast cancer death rate continues
A decades-long decline in the breast cancer death rate continues, but has begun to slow in recent years.
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Discovery of new source of cancer antigens may expand cancer vaccine capabilities
Scientists have found a common, new source of tumor mutations that could offer three levels of therapy with a cancer vaccine: 1) a broadly protective, or pan-cancer vaccine 2) cancer-type specific vaccines (e.g. breast vs. pancreatic), 3) personalized cancer vaccines based on mutations unique to an individual.
Read moreImmune therapy eliminates tumor cells in early triple negative breast cancer
Immune therapy added to chemotherapy improves pathological complete response in patients with early triple negative breast cancer, according to new results from the KEYNOTE-522 trial. Interim results from the study, which is the first phase III trial of immunotherapy in early breast cancer, also indicated an improvement in event-free survival.
Read moreCannabis study reveals how CBD offsets the psychiatric side-effects of THC
Researchers have shown for the first time the molecular mechanisms at work that cause cannabidiol, or CBD, to block the psychiatric side-effects caused by tetrahydrocannabinol (THC), the main psychoactive chemical in cannabis.
Read moreBreast cancer: New data on cohort with recurrence score 26-100 shows 93% cancer-free rate at 5 years
In the prospective TAILORx trial, 93% of women with hormone-sensitive, HER2-negative, axillary node-negative breast cancer and a high Recurrence Score 26-100 were estimated to be cancer-free at five years. This outcome was much better than expected with endocrine therapy alone. The finding adds to limited data on outcomes with a high RS of 26-100, treated with taxane and/or anthracycline-containing chemotherapy plus endocrine therapy. It adds to the body of evidence supporting use of the RS.
Read moreWhole genome sequencing could enable personalized cancer treatment
Whole genome sequencing of tumour cells could help predict the prognosis of a patient's cancer and offer clues to identify the most effective treatment, suggests an international study.
Read moreMesothelioma trial suggests immunotherapy as an alternative to chemotherapy
Patients with mesothelioma may gain similar benefit from immunotherapy as chemotherapy, and good responders may provide important clues to novel treatment for the thousands of new cases each year. New data highlight the need to understand the biological mechanisms whereby mesothelioma, which is incurable, adapts to immunotherapy in some patients but not in others, resulting in variations in treatment response.
Read moreNew blood test capable of detecting multiple types of cancer
A new blood test in development has shown ability to screen for numerous types of cancer with a high degree of accuracy, a trial of the test shows.
Read morePancreatic cancer discovery reveals how the aggressive cancer fuels its growth
A new discovery about pancreatic cancer sheds light on how the cancer fuels its growth and may help explain how promising cancer drugs work — and for whom they will fail.
Read moreFathering children by assisted reproduction linked to increased risk of prostate cancer
Men who became fathers through assisted reproduction techniques seem to be at higher risk for prostate cancer and early onset prostate cancer compared with men achieving fatherhood naturally.
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