Vitamin D and fish oil show promise in prevention of cancer death and heart attacks

The VITamin D and OmegA-3 Trial (VITAL) is the largest and most recent to test whether vitamin D or fish oil can effectively prevent cancer or cardiovascular disease. Results to date have been mixed but show promise for some outcomes, now confirmed by updated pooled (meta) analyses.

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US pediatric heart transplant waitlist policy change falls short of intended benefits

In March 2016, the Organ Procurement and Transplantation Network revised its criteria for prioritizing children awaiting heart transplantation in the US with the intention of reducing the number of deaths on the waitlist, but a new study suggests unintended consequences.

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Shorter people are at higher risk of type 2 diabetes, study shows


Short stature is associated with a higher risk of type 2 diabetes, according to a new study. Tall stature is associated with a lower risk, with each 10cm difference in height associated with a 41 percent decreased risk of diabetes in men and a 33 percent decreased risk in women.

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Defective cilia linked to heart valve birth defects

Bicuspid aortic valve (BAV), the most common heart valve birth defect, is associated with genetic variation in human primary cilia during heart valve development, report researchers. Crucial to cilia development is the exocyst, which shuttles cilia cargo to the cell membrane. Disrupting the exocyst impaired ciliogenesis and caused a spectrum of cardiac defects in zebrafish and BAV in mice.

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