How neuronal recognition of songbird calls unfolds over time
A novel computational approach sheds new light on the response of neurons in the brain of a songbird when it hears and interprets the meaning of another bird's call.
Read moreCell Biology
Unravelling an alternative mechanism of airway mucosal immunity
Researchers have identified two key proteins, ASC and NLRP3, in the maintenance of the innate immune homeostasis in the airway. These proteins do so by a caspase-1-independent mechanism, suggesting that there may be multiple mechanisms involved in protection against microbial infections.
Read moreCell-based therapies for arthritis and osteoporosis
A new report highlights the latest advances in cell-based therapies for the treatment of disorders of the musculoskeletal system, such as arthritis and osteoporosis, and it identifies key unanswered questions that should be addressed through ongoing research.
Read moreHow molecular footballs burst in an x-ray laser beam
An international research team has observed in real time how football molecules made of carbon atoms burst in the beam of an X-ray laser. The study shows the temporal course of the bursting process, which takes less than a trillionth of a second, and is important for the analysis of sensitive proteins and other biomolecules, which are also frequently studied using bright X-ray laser flashes.
Read moreResearchers investigate key component in bacteria
A protective protein that detects newly-made incomplete protein chains in higher cells is found to have a relative in bacteria. There, the protein also plays a central role in quality control which ensures that defective proteins are degraded. The functional mechanism of these Rqc2 proteins must therefore have already existed several billion years ago in the so-called last universal common ancestor. Scientists have experimentally investigated the bacterial Rqc2 relative's function.
Read moreNeurological signals from the spinal cord surprise scientists
With a study of the network between nerve and muscle cells in turtles, researchers have gained new insight into the way in which movements are generated and maintained. In the long term, the new knowledge may have an impact on the treatment of, for example, ALS and spinal cord injuries.
Read moreStudying proteins moving (relatively) slowly
Proteins keep our organs functioning, regulate our cells and are the targets for medications that treat a number of diseases, including cancers and neurological diseases. Proteins need to move in order to function. But, because the technology they used to watch proteins doesn't allow it, scientists still know very little about such motions at speeds slower than a nanosecond. That changed last month.
Read moreScientists construct energy production unit for a synthetic cell
Scientists have constructed synthetic vesicles in which ATP, the main energy carrier in living cells, is produced. The vesicles use the ATP to maintain their volume and their ionic strength homeostasis. This metabolic network will eventually be used in the creation of synthetic cells – but it can already be used to study ATP-dependent processes.
Read moreProgrammable swarmbots make flexible biological tools
Biomedical engineers have developed a new platform to create biological drugs using specially engineered bacteria that burst and release useful proteins when they sense that their capsule is becoming too crowded.
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