Innovative pancreatic cancer treatment may rev up immune system

A research team reports that combining a type of radiation therapy with immunotherapy not only cures pancreatic cancer in mice, but appears to reprogram the immune system to create an 'immune memory' in the same way that a vaccine keeps the flu away. The result is that the combination treatment also destroyed pancreatic cells that had spread to the liver, a common site for metastatic disease.

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Mapping normal breast development to better understand cancer

Breast cancer is one of the most prevalent cancers, and some forms rank among the most difficult to treat. Its various types and involvement of many different cells makes targeting such tumors difficult. Now, researchers have used a state-of-the-art technology to profile each cell during normal breast development in order to understand what goes wrong in cancer.

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Scientists have identified the presence of cancer-suppressing cells in pancreatic cancer

Researchers have identified cells containing a protein called Meflin that has a role in restraining the progression of pancreatic cancer. They have also shown that cancer progression can be controlled by artificially increasing the amount of this protein in the cells.

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The story of thalidomide continues

An international study has unveiled a detailed view of how thalidomide, one of the most notorious drugs ever developed, causes abnormalities in limb and ear development. The findings may contribute to the re-emergence of safe, or non-teratogenic, thalidomide-derived drugs as a treatment for cancer and inflammatory diseases.

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New test for thyroid cancer could prevent unnecessary surgery

Each year, thanks to inconclusive tests for thyroid cancer, thousands of people undergo unnecessary surgeries to remove part or all of their thyroids. A new test based on the unique chemical fingerprints of thyroid cancer might change that. It's faster and about two-thirds more accurate than the diagnostic tests doctors use today.

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