Researchers have discovered how a cancer-linked version of the protein mitoNEET can close voltage-dependent anion channels (VDAC), primary gateways in the outer surface of mitochondria. The researchers detail how mitoNEET regulates VDAC, and they show that the interactions between the two proteins could be disrupted by a drug that targets VDAC.
Read moreScientists have shown for the first time that severe brain cancers integrate into the brain's wiring.
Read moreScientists have discovered a signaling pathway that breast tumors exploit to metastasize to the brain.
Read moreResearchers have discovered that some cancer cells survive chemotherapy by eating their neighboring tumor cells. The study suggests that this act of cannibalism provides these cancer cells with the energy they need to stay alive and initiate tumor relapse after the course of treatment is completed.
Read moreA treatment for psoriasis could be repurposed to treat a rare but aggressive form of youth cancer, new findings suggest.
Read moreIn a small safety and feasibility clinical trial, researchers have demonstrated for the first time that senescent cells can be removed from the body using drugs termed 'senolytics.' The result was verified not only in analysis of blood but also in changes in skin and fat tissue senescent cell abundance.
Read moreResearchers have developed a new anti-cancer nanomedicine for targeted cancer chemotherapy. This new nano-tool provides a new approach to use cell-based nanomedicines for efficient cancer chemotherapy.
Read moreSelective mammography screening can provide potentially lifesaving early detection of breast cancer in men who are at high risk for the disease, according to a new landmark study.
Read moreAn inter-disciplinary team of researchers has unraveled how a toxin released by Escherichia coli (E. coli) – a human gut bacteria, is connected to colorectal cancer, offering new insights to the health impact of this prevalent bacteria and facilitating future research on the prevention of this third most common cancer worldwide.
Read moreWhile the medical community agrees immune cells inside a tumor leads to improved health outcome, for a subset of colorectal cancer patients, having too much of a good thing is a strong predictor of disease recurrence and reduced chances of survival. Scientists identify patients who could benefit from immunotherapy. This is the first report of immune infiltrated tumors with poor health outcomes and is counter to the standard belief in the field.
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