No clear link between local food and cancer risk in glassworks areas

There is no clear link between cancer incidence and locally produced food from an area with a history of glass manufacture with contaminated soil, according to a new study. A high consumption of certain local foods seems to be linked to an increased risk of certain cancers, but this probably reflects that the exposure to contaminants was higher in the past.

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Empowering cancer patients to shift their mindsets could improve care, researchers argue

A cancer diagnosis can cause a significant emotional burden for patients and their families. This may persist years into survivorship. As a result, depression and anxiety are two to three times more common in cancer patients than the general population. Experts propose that targeting cancer patients' mindsets could have an impact on their health, functioning, and well-being, and they call for more research in this field.

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Discovery of novel cancer signaling mechanism and design of new anticancer compound

Active mutations of a certain signaling receptor protein called KIT tyrosine kinase are found in several cancers, such as acute myeloid leukemia (AML). However, the different locations in the AML cells where KIT induces cancer-specific signaling remain unclear. Now, a group of scientists has aimed to answer this question by using a newly synthesized compound (along with other existing ones) that targets intracellular transport, which may offer an attractive strategy to combat cancer.

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Compound extends survival in mice with certain pediatric brain tumors

Versions of an antibiotic drug called DON first isolated from soil bacteria more than 60 years ago have shown promising signs of extending survival in mice models of especially lethal pediatric brain tumors marked by the high expression of a cancer-causing gene known as the MYC oncogene.

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Combination therapies could help treat fatal lung cancers

Combining a new class of drug with two other compounds can significantly shrink lung tumors in mice and human cancer cells, new research shows. The study looked at G12C KRAS inhibitors, a new type of drug that targets a specific mutation that can cause cells to multiply uncontrollably and lead to fast-growing cancers.

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