Possible approach to block medulloblastoma growth
Researchers have identified a potential approach to stop the growth of the most common type of brain tumor in children.
Read moreCancer
Zeroing in on how a tumor suppressor protein is cast away
Researchers have uncovered new details about several proteins implicated in tumor growth and metastasis, opening a potential avenue for the development of treatments for diseases such as breast cancer.
Read moreWhy targeted immuno-oncology drugs sometimes fail
Researchers report a discovery that helps scientists understand why some tumors lack immune cell infiltration and are therefore unresponsive to newer PD-1 targeted therapies.
Read moreClues to improve cancer immunotherapy revealed
A new study indicates a way for cancer immunotherapy to spur a more robust immune response. Such knowledge could lead to the development of better cancer vaccines and more effective immunotherapy drugs called checkpoint inhibitors.
Read moreScientists unveil the secret of cancer-associated Warburg effect
New research shows that lactate, an end product of metabolism, changes the function of an immune cell known as a macrophage, thereby rewiring it to behave differently.
Read moreSensing sweetness on a molecular level
Whether it's chocolate cake or pasta sauce, the sensation of sweetness plays a major role in the human diet and the perception of other flavors. While a lot is known about the individual proteins that signal ''sweet,'' not much is known about how the proteins work together as a receptor to accomplish this feat.
Read moreStressing cancer with spice
A new study reports how an experimental drug agent stops cancer cells from growing. A little over a decade ago, scientists first reported pentagamavumon-1 (PGV-1), an analogue of a molecule found in turmeric and that has been since discovered to have anti-cancer effects. In the new study, tests on cancer cells and animals reveal that these anti-cancer effects come from PGV-1 inhibiting a series of enzymes responsible for the metabolism of reactive oxygen species. This finding is expected to clarify how modifications to PGV-1 will lead to its use for cancer treatment.
Read moreEmbryology: How cell competition modulates morphogen gradients
Tissue patterning is an important process during embryo formation, which ensures that groups of cells are arranged in an appropriate manner that allows them to function properly.
Read moreOptoacoustic imaging shows potential for noninvasive diagnostics for thyroid disorders
A novel, noninvasive imaging technique can provide new information about thyroid disorders that will help in evaluation and diagnosis, according to an article featured in the October 2019 issue of The Journal of Nuclear Medicine.
Read moreNew organelle that helps prevent cancer discovered in our cells
Scientists have discovered a strange structure inside our cells that helps to prevent cancer by ensuring genetic material is sorted correctly as cells divide. The discovery could improve treatment for breast cancer and possibly other cancers.
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