Male and female mice have different brain cells
Scientists discover that a brain region known to control sex and violence contains rare cell types that differ in male versus female mice.
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Stem cell study offers new way to study early development and pregnancy
For the first time, researchers have created mouse blastocyst-like structures, or 'blastoids,' from a single cultured cell. The work could help advance research into development as well as inform issues around pregnancy, infertility, or health problems later in the offspring's life.
Read moreBARseq builds a better brain map
A brain mapping technique called BARseq is capable of mapping thousands of neurons in a single mouse, at single neuron resolution, while also detailing which neuron expresses what genes. It could be a game-changer for how neuroscientists look at brains.
Read moreNew insights into the structure and function of Cdc34, a target for cancer therapeutics
Researchers report they have obtained 3D structural snapshots of Cdc34 in action. Cdc34 is an enzyme important for cell cycle regulation and a target for therapeutic intervention in cancer. These structures, along with studies in human cells, have revealed key features of this enzyme important for its regulation of cell growth and activity. These unique features could present opportunities for rational design of novel cancer therapeutics.
Read moreSmoke signals: Study shows path linking nicotine addiction to increased risk for diabetes
Researchers have discovered a circuit in rats that links cigarette smoking and the risk of developing type 2 diabetes, according to a new study.
Read moreBeyond Mutation: Cause of drug resistance in a type of intestinal tumors
Researchers clarify mechanisms that allow hard-to-treat cancers to develop, and have identified strategies that could lead to new therapies.
Read morePioneering cell therapies for non-responders to current immunotherapies
New research signposts a new, less invasive approach to identify killer T lymphocytes in patients with gastrointestinal tumors with low mutational burden who are refractory to approved immune-based treatments.
Read moreNew marker for tumor aggression in neurofibromatosis type 1
A new study of tumor samples from people with the rare genetic syndrome neurofibromatosis type 1 (NF1) has uncovered novel molecular clues about which tumors are most likely to be aggressive in those with NF1. According to the researchers, the clues could advance the search for more customized and relevant treatments that spare patients exposure to treatments unlikely to work.
Read moreProgress in global cancer fight is not only possible, but achievable
The Cancer Atlas, 3rd edition, a comprehensive global overview of cancer around the globe, concludes that progress in the fight against cancer is not only possible, but achievable.
Read moreGlowing particles in the blood may help diagnose and monitor brain cancer
A chemical that has improved surgeries for brain cancer by making tumor cells fluorescent may also help doctors safely diagnose the disease and monitor its response to treatment.
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