In Alzheimer's research, scientists reveal brain rhythm role

In the years since her lab discovered that exposing Alzheimer's disease model mice to light flickering at the frequency of a key brain rhythm could stem the disorder's pathology, a neuroscientist and her team have been working to understand what the phenomenon may mean both for fighting the disease and understanding of how the brain works.

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Protein in blood protects against neuronal damage after brain hemorrhage

Patients who survive a cerebral hemorrhage may suffer delayed severe brain damage caused by free hemoglobin, which comes from red blood cells and damages neurons. Researchers have now discovered a protective protein in the body called haptoglobin, which prevents this effect.

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Aggressive form of breast cancer influenced by dual action of genes and RNA

Women with an aggressive, less-common type of breast cancer, known as triple-negative, versus a more common form of the disease, could be differentiated from each other by a panel of 17 small RNA molecules that are directly influenced by genetic alterations typically found in cancer cells.

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A blood factor involved in weight loss and aging

Aging can be delayed through lifestyle changes (physical exercise, restricting calorie intake, etc.). Researchers have elucidated the properties of a molecule in the blood – GDF11 – whose mechanisms were previously unknown. In a mouse model, they showed that this molecule could mimic the benefits of certain calorie restrictions – dietary regimens that have proven their efficacy in reducing cardiovascular disease, preventing cancer and increasing neurogenesis in the brain.

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