Possible approach to block medulloblastoma growth
Researchers have identified a potential approach to stop the growth of the most common type of brain tumor in children.
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Deep inside the brain: Unraveling the dense networks in the cerebral cortex
Mammalian brains, with their unmatched number of nerve cells and density of communication, are the most complex networks known. While methods to analyze neuronal networks sparsely have been available for decades, the dense mapping of neuronal circuits is a major scientific challenge. Researchers have now succeeded in the dense connectomic mapping of brain tissue from the cerebral cortex, and quantify the possible imprint of learning in the circuit.
Read moreGut instincts: Researchers discover first clues on how gut health influences brain health
New cellular and molecular processes underlying communication between gut microbes and brain cells have been described for the first time.
Read moreZeroing in on how a tumor suppressor protein is cast away
Researchers have uncovered new details about several proteins implicated in tumor growth and metastasis, opening a potential avenue for the development of treatments for diseases such as breast cancer.
Read moreHigh-salt diet promotes cognitive impairment through the Alzheimer-linked protein tau
Investigators sought to understand the series of events that occur between salt consumption and poor cognition and concluded that lowering salt intake and maintaining healthy blood vessels in the brain may 'stave off' dementia. Accumulation of tau deposits has been implicated in the development of Alzheimer's disease in humans.
Read moreZebrafish discovery throws new light on human hearing disorders
A study of the genetic make-up of zebrafish has provided brand new insights into the cause of congenital hearing disorders in humans.
Read moreWhy targeted immuno-oncology drugs sometimes fail
Researchers report a discovery that helps scientists understand why some tumors lack immune cell infiltration and are therefore unresponsive to newer PD-1 targeted therapies.
Read moreClues to improve cancer immunotherapy revealed
A new study indicates a way for cancer immunotherapy to spur a more robust immune response. Such knowledge could lead to the development of better cancer vaccines and more effective immunotherapy drugs called checkpoint inhibitors.
Read moreScientists unveil the secret of cancer-associated Warburg effect
New research shows that lactate, an end product of metabolism, changes the function of an immune cell known as a macrophage, thereby rewiring it to behave differently.
Read moreA possible gut-brain connection to 'chemo brain'
To test the possible relationship between the gut and chemo brain, a lab is examining chemo's effects on mice whose guts have been manipulated before treatment. One experiment involves feeding the mice antibiotics. The other relies on the universal practice among mice of eating their own and their roommates' feces.
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