Simulations characterize turbulence caused by common connection for dialysis

The complex interplay among the arteriovenous grafts, the vessels they connect, and the blood they transport has been difficult to simulate, but one new method provides a way. Researchers report simulations that reconstructed the fluid dynamics affected by the insertion of an AVG. They used a model that considered the ability of AVG tubes and blood vessels to deform and found much of the disrupted flow could be mitigated by this flexibility.

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Researchers discover new, treatable pathway known to cause hypertension in obese people

There's no question that as body weight increases, so too does blood pressure. Now, in a study of mice, researchers have revealed exactly which molecules are likely responsible for the link between obesity and blood pressure. Blocking one of these molecules — a signaling channel that's found in a tiny organ on the side of your neck — effectively lowers blood pressure in obese mice.

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Cellular senescence is associated with age-related blood clots

Cells that become senescent irrevocably stop dividing under stress, spewing out a mix of inflammatory proteins that lead to chronic inflammation as more and more of the cells accumulate over time. Researchers have identified 44 specific senescence-associated proteins that are involved in blood clotting, marking the first time that cellular senescence has been associated with age-related blood clots.

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