Exploring the effect of fasting on age-related diseases

There are many indications that fasting promotes longevity. In recent years, much attention has been devoted to so-called caloric restriction mimetics (CMRs), substances that simulate the health-promoting effects of fasting without the need of life-style change. A study reports the identification of a novel candidate CRM. The substance may prove useful in the further research for the treatment of age-related diseases.

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Sperm and egg cell 'immune response' protects koala DNA

Discovery of a type of immunity that protects koalas' DNA from viruses has importance for the survival of koalas and our fundamental understanding of evolution. A team of scientists are studying tissue samples from koalas to understand how a unique type of cell responds to retrovirus infections, which cause diseases such as chlamydia and cancer.

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Synthetic cells make long-distance calls

Synthetic biologists design transcriptional circuits that allow single-cell microbes to form networks that spur collective action, even in large communities. The work could lead to engineered microbes that treat conditions in gut microbiomes or communicate with bioelectronics.

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Unlocking the biochemical treasure chest within microbes

An international team of scientists has developed a genetic engineering tool that makes producing and analyzing microbial secondary metabolites — the basis for many important agricultural, industrial, and medical products — easier than ever before, and could even lead to breakthroughs in biomanufacturing.

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