Up-close and personal with neuronal networks

Researchers have developed an electronic chip that can perform high-sensitivity intracellular recording from thousands of connected neurons simultaneously. This breakthrough allowed them to map synaptic connectivity at an unprecedented level, identifying hundreds of synaptic connections.

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Scientists track frog-killing fungus to help curb its spread

With the help of advanced genetic testing and hundreds of frog skin swabs, an international team of researchers has created the most complete map to date of when and where different genetic variants of the frog-killing Batrachochytrium dendrobatidis have infected frog populations around the world. The investigation also uncovered a whole new genetic lineage of the fungus, one that appears to have originated in Asia and may be the oldest variant yet discovered.

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Better samples, better science: New study explores integrity of research specimens

Biological samples can be highly susceptible to changes over time, which often occur when they are removed from deep refrigeration. Degraded samples can produce spurious results in research. To address these concerns, scientists have designed a highly sensitive test that can be used to establish the integrity of blood plasma and serum, the most common biosamples used in medical research.

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How molecular footballs burst in an x-ray laser beam

An international research team has observed in real time how football molecules made of carbon atoms burst in the beam of an X-ray laser. The study shows the temporal course of the bursting process, which takes less than a trillionth of a second, and is important for the analysis of sensitive proteins and other biomolecules, which are also frequently studied using bright X-ray laser flashes.

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DNA is held together by hydrophobic forces

Researchers have disproved the prevailing theory of how DNA binds itself. It is not, as is generally believed, hydrogen bonds which bind together the 2 sides of the DNA structure. Instead, water is the key. The discovery opens doors for new understanding in research in medicine and life sciences.

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Researchers investigate key component in bacteria

A protective protein that detects newly-made incomplete protein chains in higher cells is found to have a relative in bacteria. There, the protein also plays a central role in quality control which ensures that defective proteins are degraded. The functional mechanism of these Rqc2 proteins must therefore have already existed several billion years ago in the so-called last universal common ancestor. Scientists have experimentally investigated the bacterial Rqc2 relative's function.

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