Identifying a gene for canine night blindness

Researchers have identified the gene mutation responsible for a form of night blindness in dogs. Strategies to treat this condition, which affects a layer of neurons just below the primary photoreceptor cells, could also inform treatment of other diseases that rely on targeting this cell type.

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How AIDS pathogens multiply in the body

Scientists have now succeeded in using high-resolution imaging to make visible to the millisecond how the HI virus spreads between living cells and which molecules it requires for this purpose. The researchers provide direct proof for the first time that the AIDS pathogen creates a certain lipid environment for replication.

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Earthquake in the cell

Nuclear abnormalities such as nuclear blebs and micronuclei have devastating consequences for the genetic material and are associated with cancer or ageing. Scientists now revealed that the epigenetic enzyme MOF is crucial for the morphological integrity of the mammalian nucleus. Moreover, the study characterized the epigenetic landscape of nuclear abnormalities and discovered a formerly unknown epigenetic mechanism that seems to protect cells from additional damage.

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