New human reference genome resources help capture global genetic diversity

Scientists have assembled a set of genetic sequences that enable the reference genome to better reflect global genetic diversity. The new sequences improve the utility of the human reference genome, a touchstone resource for modern genetics and genomics research.

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Opioid Rx dosages drop with state law changes

The total amount of opioids dispensed per new opioid prescription decreased by 22% in Penn Medicine outpatient practices in New Jersey after the state passed a law limiting prescriptions to a five-day supply for new opioid prescriptions. Penn Medicine implemented an electronic health record (EMR) alert, or 'nudge,' to notify clinicians if that limit had been reached.

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Mounting brain organoid research reignites ethical debate

As research involving the transplantation of human 'mini-brains' — known as brain organoids — into animals to study disease continues to expand, so do the ethical debates around the practice. A new article seeks to clarify the abilities of brain organoids and suggests an ethical framework that better defines and contextualizes these organoids and establishes thresholds for their use.

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Female surgeons earned 24% less per hour while operating compared to male surgeons

Female surgeons earned 24 per cent less per hour while operating compared to male surgeons, finds a new study, which also noted that female surgeons performed fewer of the highest-paid primary procedures than male surgeons. The study identified over 1.5 million surgical procedures claimed by 3,275 surgeons in Ontario from the beginning of 2014 until the end of 2016.

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