New mechanism controlling DNA repair identified

Deoxyribonucleic acid (DNA), is the macromolecule that holds all hereditary and genetic information. Continuously under assault, alterations and damage to DNA can lead to many different health issues, including cancer. DNA is highly regulated within cells, where multiple mechanisms are at play to repair and protect its integrity. Scientists are still investigating these mechanisms to fully comprehend how these DNA repair processes are managed. Researchers recently identified a new mechanism that controls DNA repair.

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Earthquake in the cell

Nuclear abnormalities such as nuclear blebs and micronuclei have devastating consequences for the genetic material and are associated with cancer or ageing. Scientists now revealed that the epigenetic enzyme MOF is crucial for the morphological integrity of the mammalian nucleus. Moreover, the study characterized the epigenetic landscape of nuclear abnormalities and discovered a formerly unknown epigenetic mechanism that seems to protect cells from additional damage.

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Cracking how tardigrades survive the extremes

Scientists have gained a new understanding of how tiny, ultra-resilient invertebrates known as tardigrades, or 'water bears,' are protected in extreme conditions. Tardigrades are found in water environments around the world — including mountainous, deep sea and Antarctic environments. The researchers discovered that a tardigrade protein named Dsup binds to chromatin — DNA inside cells — and forms a protective cloud against extreme survival threats such as radiation damage.

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A closer look at monogamy and polygamy in brood parasitic birds

Researchers have discovered that cowbirds conform to Bateman's Principle, despite investing no energy into parental care. Surprisingly, 75% of the cowbirds in the system were monogamous. Future research will expand upon these findings and broaden the understanding of how cowbirds might select the nests they parasitize, what role the males could play to assist the females, and why monogamy could be such a benefit.

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The flagellar hook: Making sense of bacterial motility

Researchers show how bacteria transmit motion from an inner motor to an outer tail through a flexible joint in the flagellum known as the hook. This finding could help in the fight against deadly bacterial infections. By better understanding how bacteria move, researchers may be able to improve disease prevention strategies.

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Test for life-threatening nutrient deficit is made from bacteria entrails

A pocket-sized zinc deficiency test could be taken to remote regions where masses are malnourished – no complex transport or preservation necessary. It could be evaluated on the spot, and this initial test could be expanded into more comprehensive micronutrient fieldtests.

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Mosquito eye inspires artificial compound lens

Anyone who's tried to swat a pesky mosquito knows how quickly the insects can evade a hand or fly swatter. The pests' compound eyes, which provide a wide field of view, are largely responsible for these lightning-fast actions. Now, researchers have developed compound lenses inspired by the mosquito eye that could someday find applications in autonomous vehicles, robots or medical devices.

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Breakthrough in understanding enzymes that make antibiotic for drug-resistant pathogen

One of the WHO's 3 critical priority pathogens, Acinetobacter baumannii, for which new antibiotics are urgently needed is one step closer to being tackled, as researchers have made a breakthrough in understanding the enzymes that assemble the antibiotic enacyloxin.

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