Deformed wing virus genetic diversity in US honey bees complicates search for remedies

Deformed Wing Virus (DWV), one of the leading causes of honey bee colony losses, is much more genetically diverse in the United States than previously thought. The diverse lineages of this virus are all equally bad for bees, and they make it more complicated to develop antiviral therapeutics, which could be the basis for developing a vaccine for the virus.

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Genetic risk factor for laryngeal paralysis in miniature bull terriers identified

Laryngeal paralysis is a serious and sometimes deadly disease in some dog breeds that prevents proper opening of the larynx for breathing. Specialists in canine head and neck surgery and geneticists have identify a mutation responsible for laryngeal paralysis in Miniature Bull Terriers, enabling the development of a genetic test for the disease.

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Newly discovered protein is the permit to the powerhouse of cells

Researchers report the discovery of a protein, P17/PERMIT, that is key to recycling aging and damaged mitochondria. Defective mitochondria are characteristic of a number of age-related diseases, including cancer and Alzheimer's. The MUSC team showed P17/PERMIT transports the machinery that produces ceramide, a molecule that signals old mitochondria for destruction, to the mitochondria. There, it can mass-produce ceramide at the location needed for mitochondrial regulation.

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New CRISPR genome editing system offers a wide range of versatility in human cells

A team has developed a new CRISPR genome-editing approach by combining two of the most important proteins in molecular biology — CRISPR-Cas9 and a reverse transcriptase — into a single machine.

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First report of cotton blue disease in the United States

Reported from six counties in coastal Alabama in 2017, cotton blue disease affected approximately 25% of the state's cotton crop and caused a 4% yield loss. The disease was reported again in 2018, affecting 3-100% of cotton fields in Alabama but causing only a 1% yield loss. Symptoms, which include slowed plant growth, loss of chlorophyll, and dwarfing of infected leaves, usually do not appear until last August after full bloom. To date, there are no recommended strategies for management of this disease.

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