Cheap, quick test identifies pneumonia patients at risk of respiratory failure or sepsis

Researchers have now identified specific fragments of genetic material that play a role in the development of respiratory failure and sepsis in pneumonia patients. The findings could enable doctors to test quickly for these biological markers when a patient is admitted to hospital with pneumonia, so that they could anticipate complications and provide more intensive support and monitoring.

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Three-in-one inhaler therapy can improve lung function and reduce asthma attacks

Patients with severe asthma which is not controlled with standard treatment — leaving them at risk of severe asthma attacks — could benefit from using a single inhaler combining three, instead of 2 therapies, according to two phase 3 randomized controlled trials with over 2,500 patients across 17 countries.

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Babies have fewer respiratory infections if they have well-connected bacterial networks

Microscopic bacteria, which are present in all humans, cluster together and form communities in different parts of the body, such as the gut, lungs, nose and mouth. Now, for the first time, researchers have shown the extent to which these microbial communities are linked to each other across the body, and how these networks are associated with susceptibility to respiratory infections in babies.

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African American children respond differently to asthma medications

African Americans suffer asthma more often and more severely than Caucasian patients. However, clinical trials that have shaped treatment guidelines have included few African Americans. A new report demonstrates a shortcoming of that history. Researchers report that African American children respond differently than African American adults and Caucasian adults and children to step-up therapies for inadequately controlled asthma.

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Supportive relationships in childhood leads to longer lives

Individuals raised in families with higher socioeconomic status were more optimistic in midlife, and in turn, lived longer. Those who experienced more psychosocial stressors, such as parental death, frequent moves and harsh discipline, tended to encounter more stressful life events in midlife, and had greater risk of dying early.

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