A new therapeutic being tested is showing early promise as a more effective treatment that could help nearly half of patients with Duchenne muscular dystrophy (DMD). The treatment — a cocktail of DNA-like molecules — results in dramatic regrowth of a protein called dystrophin, which acts as a support beam to keep muscles strong. The protein is virtually absent in those with DMD.
Read moreFor new diabetes medications, in which one drug aims to address the excess of lipids and glucose in the blood, the therapeutic benefits, while great, frequently are accompanied by dangerous toxic effects to the heart. Why and how these drugs cause heart dysfunction in diabetes patients has been unclear. Now, scientists show that certain diabetes drugs have a profound toxic effect on the generation and function of mitochondria.
Read moreIn the video game industry, the ability for gaming companies to track and respond to gamers' post-purchase play opens up new opportunities to enhance gamer engagement and retention and increase video game revenue.
Read moreA metabolic imbalance in some cancer patients following treatment with a checkpoint inhibitor drug, nivolumab, is associated with resistance to the immunotherapy agent and shorter survival, report scientists.
Read moreIn a new study of adolescent and adult athletes, researchers have found evidence of damage to the brain's protective barrier, without a reported concussion.
Read moreMichigan State University scientists have invented a new way to monitor chemotherapy concentrations, which is more effective in keeping patients' treatments within the crucial therapeutic window.
Read moreResearchers have developed a novel tool that will enable user-experience designers to create more effective, personalized games and marketing campaigns.
Read moreExpanding Medicaid to more low-income adults helped many of them feel healthier, and do a better job at work or a job search, in just one year after they got their new health coverage, a new study finds. But people with behavioral health conditions, including mental health disorders such as depression or addiction to alcohol or drugs, got an especially big boost in many health and work-related measures.
Read moreIntestinal epithelial cells (IECs) are exposed to diverse types of environmental stresses such as bacteria and toxins, but the mechanisms by which epithelial cells sense stress are not well understood. New research has found that Nox-ROS-ASK1-MKK3-p38 signaling in IECs integrates various stresses to facilitate intestinal regeneration.
Read moreThis major step forward in organoid development could sharply accelerate the concept of precision medicine and someday lead to transplantable tissues grown in labs.
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